PLEKHG4 Antibody

Product Specifications

Background

The protein encoded by this gene can function as a guanine nucleotide exchange factor (GEF) and may play a role in intracellular signaling and cytoskeleton dynamics at the Golgi apparatus. Polymorphisms in the region of this gene have been found to be associated with spinocerebellar ataxia in some study populations. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

25894

Swiss Prot

Q58EX7

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 710-1010 of human PLEKHG4 (NP_001123199.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

Affinity purification

Positive Control

Rat testis

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 131kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PLEKHG4

NCBI Official Name

Pleckstrin homology and RhoGEF domain containing G4

NCBI Organism

Homo sapiens

Other Product Names

ARHGEF44, PRTPHN1, SCA4, puratrophin-1, PH domain-containing family G member 4, Purkinje cell atrophy associated protein 1, pleckstrin homology domain containing, family G (with RhoGef domain) member 4