PROZ Antibody
Product Specifications
Background
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
NCBI Gene ID
8858
Swiss Prot
P22891
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 48kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PROZ
Positive Control 2
293T
Positive Control 3
Mouse kidney
Positive Control 4
Rat liver
Positive Control 5
Rat kidney
NCBI Official Name
Protein Z, vitamin K-dependent plasma glycoprotein
NCBI Organism
Homo sapiens
Other Product Names
PROZ, Vitamin K-dependent protein Z, Protein Z, PZ
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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