RAPGEF1 Antibody

Product Specifications

Background

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.

NCBI Gene ID

2889

Swiss Prot

Q13905

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_941372.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Fragment

IgG

Symbol

RAPGEF1

NCBI Official Name

Rap guanine nucleotide exchange factor 1

NCBI Organism

Homo sapiens

Other Product Names

C3G, GRF2, rap guanine nucleotide exchange factor 1, CRK SH3-binding GNRP, Rap guanine nucleotide exchange factor (GEF) 1, guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)