RARB Antibody
Product Specifications
Background
This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. Alternate promoter usage and differential splicing result in multiple transcript variants.
NCBI Gene ID
5915
Swiss Prot
P10826
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human RARB
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction, Transcription
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 60kDa
Fragment
IgG
Symbol
RARB
Positive Control 2
BT-474
Positive Control 3
NCI-H460
NCBI Official Name
Retinoic acid receptor, beta
NCBI Organism
Homo sapiens
Other Product Names
RARB, HAP, NR1B2, RRB2, MCOPS12
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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