DiMethyl-DNMT3A-K44 pAb
Product Specifications
Background
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
NCBI Gene ID
13435
Swiss Prot
O88508
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic dimethylated peptide around K44 of mouse DNMT3A (NP_031898.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
Methylated
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Fragment
IgG
Applications Notes
IF: 1:50 - 1:200
Symbol
DNMT3A K44me2
NCBI Official Name
DNA methyltransferase 3A
NCBI Organism
Mus musculus
Other Product Names
MmuIIIA, DNA (cytosine-5) -methyltransferase 3A, DNA MTase MmuIIIA, DNA methyltransferase MmuIIIA
Tested Applications
IF
Physical Properties
Liquid
Frequently Asked Questions
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