CHRM1 Antibody
Product Specifications
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
NCBI Gene ID
1128
Swiss Prot
P11229
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human CHRM1 (NP_000729.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-358
Calculated Molecular Weight
Observed: 51kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CHRM1
Positive Control 2
HepG2
NCBI Official Name
Cholinergic receptor, muscarinic 1
NCBI Organism
Homo sapiens
Other Product Names
CHRM1, cholinergic receptor, muscarinic 1, HM1, M1, MGC30125, muscarinic acetylcholine receptor M1, M1R
Tested Applications
WB, IHC
Physical Properties
Liquid
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