HSCB Antibody
Product Specifications
Background
This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
NCBI Gene ID
150274
Swiss Prot
Q8IWL3
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human HSCB (NP_741999.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-347
Calculated Molecular Weight
Observed: 27kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
HSCB
Positive Control 2
U-87MG
Positive Control 3
LO2
Positive Control 4
SGC-7901
NCBI Official Name
HscB mitochondrial iron-sulfur cluster cochaperone
NCBI Organism
Homo sapiens
Other Product Names
DNAJC2HSC2JAC1, iron-sulfur cluster co-chaperone protein HscB, DnaJ (Hsp40) homolog, subfamily C, member 2HscB iron-sulfur cluster co-chaperone homolog, HscB mitochondrial iron-sulfur cluster co-chaperone, J-type co-chaperone HSC2epididymis secretory sperm binding protein, iron-sulfur cluster co-chaperone protein HscB, mitochondrial
Tested Applications
WB
Physical Properties
Liquid
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