HSCB Antibody

Product Specifications

Background

This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

150274

Swiss Prot

Q8IWL3

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human HSCB (NP_741999.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 27kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

HSCB

Positive Control 2

U-87MG

Positive Control 3

LO2

Positive Control 4

SGC-7901

NCBI Official Name

HscB mitochondrial iron-sulfur cluster cochaperone

NCBI Organism

Homo sapiens

Other Product Names

DNAJC2HSC2JAC1, iron-sulfur cluster co-chaperone protein HscB, DnaJ (Hsp40) homolog, subfamily C, member 2HscB iron-sulfur cluster co-chaperone homolog, HscB mitochondrial iron-sulfur cluster co-chaperone, J-type co-chaperone HSC2epididymis secretory sperm binding protein, iron-sulfur cluster co-chaperone protein HscB, mitochondrial