STARD4 Antibody
Product Specifications
Background
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) .
NCBI Gene ID
134429
Swiss Prot
Q96DR4
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-342
Calculated Molecular Weight
Observed: 24kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
STARD4
Positive Control 2
Rat liver
NCBI Official Name
StAR related lipid transfer domain containing 4
NCBI Organism
Homo sapiens
Other Product Names
StAR-related lipid transfer protein 4, START domain containing 4, sterol regulated, START domain-containing protein 4, StAR-related lipid transfer (START) domain containing 4
Tested Applications
WB
Physical Properties
Liquid
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