STARD4 Antibody

Product Specifications

Background

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE) -binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423) . Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617) . STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]) .

NCBI Gene ID

134429

Swiss Prot

Q96DR4

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human STARD4 (NP_001294986.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse kidney

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 24kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

STARD4

Positive Control 2

Rat liver

NCBI Official Name

StAR related lipid transfer domain containing 4

NCBI Organism

Homo sapiens

Other Product Names

StAR-related lipid transfer protein 4, START domain containing 4, sterol regulated, START domain-containing protein 4, StAR-related lipid transfer (START) domain containing 4