PROS1 Antibody

Product Specifications

Background

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

NCBI Gene ID

5627

Swiss Prot

P07225

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 405-676 of human PROS1 (NP_000304.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 75kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PROS1

Positive Control 2

HeLa

Positive Control 3

293T

Positive Control 4

Mouse liver

Positive Control 5

Mouse kidney

Positive Control 6

Rat liver

NCBI Official Name

Protein S

NCBI Organism

Homo sapiens

Other Product Names

PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6, vitamin K-dependent protein S, protein S (alpha), protein Sa, vitamin K-dependent plasma protein S