MYOC Antibody
Product Specifications
Background
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR) . The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
NCBI Gene ID
4653
Swiss Prot
Q99972
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 245-504 of human MYOC (NP_000252.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Affinity purification
Positive Control
Raji
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 65kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MYOC
Positive Control 2
U-937
Positive Control 3
BT-474
Positive Control 4
Mouse brain
NCBI Official Name
Myocilin, trabecular meshwork inducible glucocorticoid response
NCBI Organism
Homo sapiens
Other Product Names
MYOC, GLC1A, JOAG, JOAG1, Myocilin, TIGR, GPOA
Tested Applications
WB
Physical Properties
Liquid
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