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NGLY1 Antibody

Product Specifications

Background

This gene encodes an enzyme that catalyzes hydrolysis of an N (4) - (acetyl-beta-D-glucosaminyl) asparagine residue to N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. The encoded enzyme may play a role in the proteasome-mediated degradation of misfolded glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

55768

Swiss Prot

Q96IV0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human NGLY1 (NP_060767.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 74kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

NGLY1

Positive Control 2

Raji

Positive Control 3

Mouse brain

Positive Control 4

Mouse liver

Positive Control 5

Rat testis

NCBI Official Name

N-glycanase 1

NCBI Organism

Homo sapiens

Other Product Names

CDDG, CDG1V, PNG1, PNGase, peptide-N (4) - (N-acetyl-beta-glucosaminyl) asparagine amidase, hPNGase, peptide:N-glycanase

Tested Applications

WB

Physical Properties

Liquid

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