MMADHC Antibody
Product Specifications
Background
This gene encodes a mitochondrial protein that is involved in an early step of vitamin B12 metabolism. Vitamin B12 (cobalamin) is essential for normal development and survival in humans. Mutations in this gene cause methylmalonic aciduria and homocystinuria type cblD (MMADHC), a disorder of cobalamin metabolism that is characterized by decreased levels of the coenzymes adenosylcobalamin and methylcobalamin. Pseudogenes have been identified on chromosomes 11 and X.
NCBI Gene ID
27249
Swiss Prot
Q9H3L0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human MMADHC (NP_056517.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 33kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
MMADHC
Positive Control 2
NIH/3T3
Positive Control 3
HeLa
Positive Control 4
MCF7
NCBI Official Name
Methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
NCBI Organism
Homo sapiens
Other Product Names
C2orf25, CL25022, cblD, C2orf25
Tested Applications
WB
Physical Properties
Liquid
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