RGS17 Antibody
Product Specifications
Background
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
NCBI Gene ID
26575
Swiss Prot
Q9UGC6
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 45-130 of human RGS17 (NP_036551.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 24kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
RGS17
Positive Control 2
Rat brain
NCBI Official Name
Regulator of G-protein signaling 17
NCBI Organism
Homo sapiens
Other Product Names
RGS17, RGSZ2, RGS-17, regulator of G-protein signalling 17, hRGS17
Tested Applications
WB
Physical Properties
Liquid
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