ME3 Antibody
Product Specifications
Background
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP (+) -dependent isoform, a mitochondrial NADP (+) -dependent isoform, and a mitochondrial NAD (+) -dependent isoform. This gene encodes a mitochondrial NADP (+) -dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
NCBI Gene ID
10873
Swiss Prot
Q16798
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 505-604 of human ME3 (NP_001014811.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 78kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ME3
Positive Control 2
293T
Positive Control 3
Mouse brain
Positive Control 4
Mouse heart
Positive Control 5
Mouse kidney
Positive Control 6
Rat brain
NCBI Official Name
Malic enzyme 3
NCBI Organism
Homo sapiens
Other Product Names
NADP-ME, NADP-dependent malic enzyme, mitochondrial, malate dehydrogenase (oxaloacetate-decarboxylating) (NADP (+) ), malic enzyme 3, NADP (+) -dependent, mitochondrial, malic enzyme, NADP+-dependent, mitochondrial, mitochondrial NADP (+) -dependent malic enzyme 3, pyruvic-malic carboxylase
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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