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A2M Antibody

Product Specifications

Background

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

NCBI Gene ID

2

Swiss Prot

P01023

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human A2M (NP_000005.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

SH-SY5Y

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=16-203

Calculated Molecular Weight

Observed: 160kDa

Fragment

IgG

Symbol

A2M

Positive Control 2

Mouse kidney

Positive Control 3

Mouse ovary

Positive Control 4

Rat spinal cord

NCBI Official Name

Alpha-2-macroglobulin

NCBI Organism

Homo sapiens

Other Product Names

A2M, alpha-2-macroglobulin, A2MD, CPAMD5, FWP007, S863-7, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, alpha-2-M

Tested Applications

WB, IF

Physical Properties

Liquid

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