A2M Antibody
Product Specifications
Background
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
NCBI Gene ID
2
Swiss Prot
P01023
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1155-1474 of human A2M (NP_000005.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 160kDa
Fragment
IgG
Symbol
A2M
Positive Control 2
Mouse kidney
Positive Control 3
Mouse ovary
Positive Control 4
Rat spinal cord
NCBI Official Name
Alpha-2-macroglobulin
NCBI Organism
Homo sapiens
Other Product Names
A2M, alpha-2-macroglobulin, A2MD, CPAMD5, FWP007, S863-7, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, alpha-2-M
Tested Applications
WB, IF
Physical Properties
Liquid
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