IL10RB Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21.

NCBI Gene ID

3588

Swiss Prot

Q08334

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human IL10RB (NP_000619.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Chemokines & Cytokines, Immunology, Innate Immunity, Signal Transduction

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 36kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

IL10RB

Positive Control 2

293T

Positive Control 3

Jurkat

Positive Control 4

Mouse skeletal muscle

Positive Control 5

Rat heart

Positive Control 6

Rat liver

NCBI Official Name

Interleukin 10 receptor subunit beta

NCBI Organism

Homo sapiens

Other Product Names

CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2, interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10RB, cytokine receptor class-II CRF2-4, cytokine receptor class-II member 4, cytokine receptor family 2 member 4, cytokine receptor family II, member 4, interleukin 10 receptor, beta, interleukin-10 receptor subunit 2