CHRM2 Antibody
Product Specifications
Background
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
NCBI Gene ID
1129
Swiss Prot
P08172
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human CHRM2 (NP_001006629.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-170
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Symbol
CHRM2
Positive Control 2
HepG2
NCBI Official Name
Cholinergic receptor, muscarinic 2
NCBI Organism
Homo sapiens
Other Product Names
7TM receptor, cholinergic receptor, muscarinic 2, CHRM2, FLJ43243, HM2, MGC120006, MGC120007, muscarinic acetylcholine receptor M2, muscarinic M2 receptor, OTTHUMP00000208393, OTTHUMP00000208394, OTTHUMP00000208395, OTTHUMP00000208396
Tested Applications
WB, IF
Physical Properties
Liquid
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