ETV6 Antibody
Product Specifications
Background
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
NCBI Gene ID
2120
Swiss Prot
P41212
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ETV6 (NP_001978.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Transcription
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 55kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
ETV6
Positive Control 2
Mouse lung
Positive Control 3
Mouse spleen
Positive Control 4
Rat testis
NCBI Official Name
Ets variant 6
NCBI Organism
Homo sapiens
Other Product Names
ETV6, TEL, TEL/ABL
Tested Applications
WB
Physical Properties
Liquid
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