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TSPO Antibody

Product Specifications

Background

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

NCBI Gene ID

706

Swiss Prot

P30536

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human TSPO (NP_000705.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Mouse testis

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 19kDa

Fragment

IgG

Symbol

TSPO

NCBI Official Name

Translocator protein (18kDa)

NCBI Organism

Homo sapiens

Other Product Names

TSPO, translocator protein (18 kDa), BZRP, DBI, IBP, MBR, PBR, PKBS, PTBR, mDRC, pk18, OTTHUMP00000028891, benzodiazapine receptor (peripheral), benzodiazepine peripheral binding site, mitochondrial benzodiazepine receptor, peripheral benzodiazepine receptor, peripheral-type benzodiazepine receptor

Tested Applications

WB, IF

Physical Properties

Liquid

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