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CDK9 Antibody

Product Specifications

Background

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

NCBI Gene ID

1025

Swiss Prot

P50750

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 153-372 of human CDK9 (NP_001252.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Immunology, Signal Transduction

Purification

Affinity purification

Positive Control

A549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 40kDa

Fragment

IgG

Symbol

CDK9

Positive Control 2

HeLa

Positive Control 3

U-251MG

Positive Control 4

Raji

Positive Control 5

BT-474

Positive Control 6

Mouse spleen

NCBI Official Name

Cyclin-dependent kinase 9

NCBI Organism

Homo sapiens

Other Product Names

CDK9, RP11-228B15.5, C-2k, CDC2L4, PITALRE, TAK, CTK1

Tested Applications

WB, IHC, IF, IP

Physical Properties

Liquid

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