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PDE10A Antibody

Product Specifications

Background

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.

NCBI Gene ID

10846

Swiss Prot

Q9Y233

Host

Rabbit

Reactivity

Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 23-200 of human PDE10A (NP_001124162.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Rat brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 88kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PDE10A

NCBI Official Name

Phosphodiesterase 10A

NCBI Organism

Homo sapiens

Other Product Names

ADSD2, HSPDE10A, IOLOD, LINC0047319, PDE10A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, 3',5' cAMP/cGMP phosphodiesterase, dJ416F21.1 (phosphodiesterase 10A), phosphodiesterase 10A1 (PDE10A1), phosphodiesterase 10A7 (PDE10A7)

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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