KIF7 Antibody
Product Specifications
Background
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
NCBI Gene ID
374654
Swiss Prot
Q2M1P5
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 150kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
KIF7
Positive Control 2
LO2
Positive Control 3
A-549
NCBI Official Name
Kinesin family member 7
NCBI Organism
Homo sapiens
Other Product Names
ACLS, AGBK, HLS2, JBTS12, UNQ34kinesin-like protein KIF7, EQYK340
Tested Applications
WB
Physical Properties
Liquid
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