TMEM67 Antibody
Product Specifications
Background
The protein encoded by this gene localizes to the primary cilium and to the plasma membrane. The gene functions in centriole migration to the apical membrane and formation of the primary cilium. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6) .
NCBI Gene ID
91147
Swiss Prot
Q5HYA8
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 780-940 of human TMEM67 (NP_714915.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
Mouse brain
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 115kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
TMEM67
Positive Control 2
Rat brain
Positive Control 3
Rat kidney
NCBI Official Name
Transmembrane protein 67
NCBI Organism
Homo sapiens
Other Product Names
JBTS6, MECKELIN, MKS3, NPHP11, TNEM67, meckelin, meckel syndrome type 3 protein
Tested Applications
WB
Physical Properties
Liquid
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