PIGP Antibody

Product Specifications

Background

This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI) -anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI) . This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described.

NCBI Gene ID

51227

Swiss Prot

P57054

Host

Rabbit

Reactivity

Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 25-158 of human PIGP (NP_710148.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

Mouse brain

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 22kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

PIGP

NCBI Official Name

Phosphatidylinositol glycan anchor biosynthesis class P

NCBI Organism

Homo sapiens

Other Product Names

DCRC, DCRC-S, DSCR5, DSRC, EIEE55, PIG-P, phosphatidylinositol N-acetylglucosaminyltransferase subunit P, Down syndrome critical region gene 5, Down syndrome critical region protein 5, Down syndrome critical region protein C, phosphatidylinositol glycan, class P, phosphatidylinositol-glycan biosynthesis class P protein, phosphatidylinositol-n-acetylglucosaminyltranferase subunit