RASGRP2 Antibody
Product Specifications
Background
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.
NCBI Gene ID
10235
Swiss Prot
Q7LDG7
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RASGRP2 (NP_722541.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=16-023
Calculated Molecular Weight
Observed: 69kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
RASGRP2
Positive Control 2
LO2
NCBI Official Name
RAS guanyl releasing protein 2
NCBI Organism
Homo sapiens
Other Product Names
CALDAG-GEFI, CDC25L, RAS guanyl-releasing protein 2, F25B3.3 kinase-like protein, RAS guanyl nucleotide-releasing protein 2, RAS guanyl releasing protein 2 (calcium and DAG-regulated), calcium and DAG-regulated guanine nucleotide exchange factor I, calcium and diacylglycerol-regulated guanine nucleotide exchange factor I, cdc25-like protein, guanine exchange factor MCG7
Tested Applications
WB
Physical Properties
Liquid
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