RASGRP2 Antibody

Product Specifications

Background

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

NCBI Gene ID

10235

Swiss Prot

Q7LDG7

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RASGRP2 (NP_722541.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 69kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

RASGRP2

Positive Control 2

LO2

NCBI Official Name

RAS guanyl releasing protein 2

NCBI Organism

Homo sapiens

Other Product Names

CALDAG-GEFI, CDC25L, RAS guanyl-releasing protein 2, F25B3.3 kinase-like protein, RAS guanyl nucleotide-releasing protein 2, RAS guanyl releasing protein 2 (calcium and DAG-regulated), calcium and DAG-regulated guanine nucleotide exchange factor I, calcium and diacylglycerol-regulated guanine nucleotide exchange factor I, cdc25-like protein, guanine exchange factor MCG7