PRG4 Antibody

Product Specifications

Background

The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants.

NCBI Gene ID

10216

Swiss Prot

Q92954

Host

Rabbit

Reactivity

Human, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1264-1363 of human PRG4 (NP_001121180.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

LO2

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 150kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

PRG4

NCBI Official Name

Proteoglycan 4

NCBI Organism

Homo sapiens

Other Product Names

PRG4, proteoglycan 4, CACP, FLJ32635, HAPO, JCAP, MSF, SZP, bG174L6.2, Jacobs camptodactyly-arthropathy-pericarditis syndrome, articular superficial zone protein, bG174L6.2 (MSF: megakaryocyte stimulating factor), camptodactyly, arthropathy, coxa vara