ADAMTS1 Antibody
Product Specifications
Background
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of this gene may be associated with various inflammatory processes as well as development of cancer cachexia. This gene is likely to be necessary for normal growth, fertility, and organ morphology and function.
NCBI Gene ID
9510
Swiss Prot
Q9UHI8
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 718-967 of human ADAMTS1 (NP_008919.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse kidney
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 105kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
ADAMTS1
Positive Control 2
Mouse brain
Positive Control 3
Mouse liver
Positive Control 4
Rat brain
Positive Control 5
Rat liver
NCBI Official Name
ADAM metallopeptidase with thrombospondin type 1 motif, 1
NCBI Organism
Homo sapiens
Other Product Names
ADAMTS1, ADAM-TS, ADAMTS-1, ADAM-TS 1, C3-C5, ADAM-TS1, METH-1, METH1, KIAA1346
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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