SUCLG1 Antibody

Product Specifications

Background

This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.

NCBI Gene ID

8802

Swiss Prot

P53597

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 41-346 of human SUCLG1 (NP_003840.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Signal Transduction

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 26-36kDa

Fragment

IgG

Applications Notes

WB: 1:200 - 1:2000

Symbol

SUCLG1

Positive Control 2

HepG2

Positive Control 3

A-549

Positive Control 4

Mouse thymus

Positive Control 5

Mouse brain

Positive Control 6

Mouse heart

NCBI Official Name

Succinate-CoA ligase alpha subunit

NCBI Organism

Homo sapiens

Other Product Names

GALPHA, MTDPS9, SUCLA1, succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, SCS-alpha, succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial, succinyl-CoA synthetase subunit alpha