ARL2BP Antibody

Product Specifications

Background

ADP-ribosylation factor (ARF) -like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity.

NCBI Gene ID

23568

Swiss Prot

Q9Y2Y0

Host

Rabbit

Reactivity

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ARL2BP (NP_036238.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

U-251MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 19kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

ARL2BP

Positive Control 2

MCF7

NCBI Official Name

ADP ribosylation factor like GTPase 2 binding protein

NCBI Organism

Homo sapiens

Other Product Names

BART, BART1, RP66, ADP-ribosylation factor-like protein 2-binding protein, ADP-ribosylation factor like 2 binding protein, ARF-like 2-binding protein, ARL2-binding protein, Arf-like 2 binding protein BART1, binder of ARF2 protein 1, binder of Arl Two, binder of Arl2, retinitis pigmentosa 66 (autosomal recessive)