HEY2 Antibody

Product Specifications

Background

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH) -type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.

NCBI Gene ID

23493

Swiss Prot

Q9UBP5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human HEY2 (NP_036391.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Stem Cell, Transcription

Purification

Affinity purification

Positive Control

A-549

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 36kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

HEY2

Positive Control 2

K562

Positive Control 3

MCF7

Positive Control 4

Mouse brain

Positive Control 5

Rat heart

NCBI Official Name

Hes-related family bHLH transcription factor with YRPW motif 2

NCBI Organism

Homo sapiens

Other Product Names

HEY2, OTTHUMP00000017138, MGC10720, HRT2, HES-related repressor protein 1, HESR2, HERP1, hairy-related transcription factor 2, hairy/enhancer-of-split related with YRPW motif 2, GRL, GRIDLOCK, CHF1, cardiovascular basic helix-loop-helix factor 1, bHLHb32, BHLHB32, HERP