TAS2R38 Antibody

Product Specifications

Background

This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant) .

NCBI Gene ID

5726

Swiss Prot

P59533

Host

Rabbit

Reactivity

Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 150-250 of human TAS2R38 (NP_789787.4) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

Rat thymus

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 38kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

TAS2R38

NCBI Official Name

Taste 2 receptor member 38

NCBI Organism

Homo sapiens

Other Product Names

PTC, T2R38, T2R61, THIOT, taste receptor type 2 member 38, PTC bitter taste receptor, taste receptor type 2 member 61, taste receptor, type 2, member 38