PDE1C Antibody
Product Specifications
Background
This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
NCBI Gene ID
5137
Swiss Prot
Q14123
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 435-634 of human PDE1C (NP_001177985.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Affinity purification
Positive Control
HepG2
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 81kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PDE1C
Positive Control 2
Mouse heart
Positive Control 3
Mouse brain
Positive Control 4
Mouse testis
Positive Control 5
Rat heart
Positive Control 6
Rat brain
NCBI Official Name
Phosphodiesterase 1C, calmodulin-dependent 70kDa
NCBI Organism
Homo sapiens
Other Product Names
PDE1A, HCAM1, HSPDE1A, MGC26303, Hcam3
Tested Applications
WB
Physical Properties
Liquid
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