DCN Antibody

Product Specifications

Background

This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

NCBI Gene ID

1634

Swiss Prot

P07585

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 31-359 of human DCN (NP_598010.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction, Stem Cell

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 45kDa

Fragment

IgG

Symbol

DCN

Positive Control 2

A-549

NCBI Official Name

Decorin

NCBI Organism

Homo sapiens

Other Product Names

Small leucine-rich protein 1B, proteoglycan core protein, dermatan sulphate proteoglycans II, decorin proteoglycan, bone proteoglycan II, SLRR1B, PGS2, PGII, PG40, DSPG2, CSCD, decorin, DCN