CYP11B1 Antibody
Product Specifications
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.
NCBI Gene ID
1584
Swiss Prot
P15538
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-847
Fragment
IgG
Applications Notes
IF: 1:50 - 1:200
Symbol
CYP11B1
NCBI Official Name
Cytochrome P450 family 11 subfamily B member 1
NCBI Organism
Homo sapiens
Other Product Names
CPN1, CYP11B, FHI, P450C11, cytochrome P450 11B1, mitochondrial, CYPXIB1, cytochrome P-450c11, cytochrome P45family 11, subfamily B, polypeptide 1, cytochrome P45subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 1, cytochrome P450C11, cytochrome p450 XIB1, steroid 11-beta-hydroxylase, steroid 11-beta-monooxygenase
Tested Applications
IF
Physical Properties
Liquid
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