UNC5B Antibody
Product Specifications
Background
This gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin-1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro- and anti-apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.
NCBI Gene ID
219699
Swiss Prot
Q8IZJ1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 290-377 of human UNC5B (NP_734465.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-814
Calculated Molecular Weight
Observed: 104kDa
Fragment
IgG
Symbol
UNC5B
Positive Control 2
A-549
Positive Control 3
293T
Positive Control 4
Mouse brain
Positive Control 5
Mouse lung
Positive Control 6
Mouse kidney
NCBI Official Name
Unc-5 homolog B (C. elegans)
NCBI Organism
Homo sapiens
Other Product Names
6330415E02Rik, A630020F16, D10Bwg0792e, netrin receptor UNC5B, protein unc-5 homolog 2, protein unc-5 homolog B, unc5 homolog 2, unc-5 homolog 2, unc-5 homolog B (C. elegans), Unc5b, Unc5h2 , P53RDL1, UNC5H2, UNQ1883/PRO4326
Tested Applications
WB, IF
Physical Properties
Liquid
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