TMX1 Antibody

Product Specifications

Background

This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and one transmembrane domain. Unlike most members of this gene family, it lacks a C-terminal ER-retention sequence. The mature membrane-bound protein can both oxidize and reduce disulfide bonds and acts selectively on membrane-associated polypeptides.

NCBI Gene ID

81542

Swiss Prot

Q9H3N1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 210-280 of human TMX1 (NP_110382.3) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cell Cycle, Signal Transduction

Purification

Affinity purification

Positive Control

293T

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 35kDa

Fragment

IgG

Symbol

TMX1

Positive Control 2

LO2

Positive Control 3

HeLa

Positive Control 4

Jurkat

NCBI Official Name

Thioredoxin-related transmembrane protein 1

NCBI Organism

Homo sapiens

Other Product Names

TXNDC, thioredoxin domain containing 1, TMX, TXNDC1, DKFZP564E1962, thioredoxin domain-containing, thioredoxin-related transmembrane protein, TXNDC, PSEC0085, UNQ235/PRO268