HERC5 Antibody
Product Specifications
Background
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.
NCBI Gene ID
51191
Swiss Prot
Q9UII4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 360-700 of human HERC5 (NP_057407.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 117kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
HERC5
Positive Control 2
OVCAR3
Positive Control 3
HT-1080
Positive Control 4
Mouse kidney
Positive Control 5
Rat testis
NCBI Official Name
HECT and RLD domain containing E3 ubiquitin protein ligase 5
NCBI Organism
Homo sapiens
Other Product Names
HERC5, CEB1, CEBP1
Tested Applications
WB
Physical Properties
Liquid
Curated Selection
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