PABPC1 Antibody
Product Specifications
Background
This gene encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation; it is also required for poly (A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
NCBI Gene ID
26986
Swiss Prot
P11940
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PABPC1 (NP_002559.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 71kDa
Fragment
IgG
Symbol
PABPC1
Positive Control 2
HT-29
Positive Control 3
HeLa
Positive Control 4
Mouse brain
Positive Control 5
Rat lung
NCBI Official Name
Poly (A) binding protein, cytoplasmic 1
NCBI Organism
Homo sapiens
Other Product Names
PABPC1, PAB1, PABP, PABP1, PABPC2, PABPL1
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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