G3BP1 Antibody
Product Specifications
Background
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
10146
Swiss Prot
Q13283
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 131-330 of human G3BP1 (NP_938405.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
A-431
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 68kDa
Fragment
IgG
Symbol
G3BP1
Positive Control 2
HeLa
Positive Control 3
293T
Positive Control 4
Jurka
Positive Control 5
MCF7
NCBI Official Name
GTPase activating protein (SH3 domain) binding protein 1
NCBI Organism
Homo sapiens
Other Product Names
G3BP, G3BP, HDH-VIII
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
Curated Selection
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