UNC5C Antibody
Product Specifications
Background
This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig) -like domains and 2 type I thrombospondin motifs in the extracellular region.
NCBI Gene ID
8633
Swiss Prot
O95185
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-360 of human UNC5C (NP_003719.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 103kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
UNC5C
Positive Control 2
293T
Positive Control 3
Mouse brain
Positive Control 4
Mouse lung
Positive Control 5
Rat brain
NCBI Official Name
Unc-5 homolog C (C. elegans)
NCBI Organism
Homo sapiens
Other Product Names
Unc5C, unc5 (C.elegans homolog) c, homolog of C. elegans transmembrane receptor Unc5, UNC5H3, unc-5 homolog C (C. elegans), UNC5C
Tested Applications
WB
Physical Properties
Liquid
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