PSMB7 Antibody

Product Specifications

Background

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.

NCBI Gene ID

5695

Swiss Prot

Q99436

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 44-200 of human PSMB7 (NP_002790.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

Affinity purification

Positive Control

HeLa

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 30kDa

Fragment

IgG

Symbol

PSMB7

Positive Control 2

293T

Positive Control 3

Mouse heart

Positive Control 4

Mouse testis

Positive Control 5

Mouse brain

Positive Control 6

Rat testis

NCBI Official Name

Proteasome (prosome, macropain) subunit, beta type, 7

NCBI Organism

Homo sapiens

Other Product Names

PSMB7, proteasome subunit Z, proteasome subunit alpha, proteasome catalytic subunit 2, proteasome beta 7 subunit, proteasome (prosome, macropain) subunit, beta type, 7, multicatalytic endopeptidase complex chain Z, macropain chain Z, Z