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GNAQ Antibody

Product Specifications

Background

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

NCBI Gene ID

2776

Swiss Prot

P50148

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human GNAQ (NP_002063.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

Affinity purification

Positive Control

DU145

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=15-694

Calculated Molecular Weight

Observed: 42kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

GNAQ

Positive Control 2

OVCAR3

Positive Control 3

HT-29

Positive Control 4

U-251MG

Positive Control 5

LO2

Positive Control 6

Mouse brain

NCBI Official Name

Guanine nucleotide binding protein (G protein), q polypeptide

NCBI Organism

Homo sapiens

Other Product Names

GAQ, G-ALPHA-q, guanine nucleotide binding protein (G protein), q polypeptide, GNAQ, GAQ

Tested Applications

WB

Physical Properties

Liquid

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