GNAQ Antibody
Product Specifications
Background
This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.
NCBI Gene ID
2776
Swiss Prot
P50148
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-359 of human GNAQ (NP_002063.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 42kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
GNAQ
Positive Control 2
OVCAR3
Positive Control 3
HT-29
Positive Control 4
U-251MG
Positive Control 5
LO2
Positive Control 6
Mouse brain
NCBI Official Name
Guanine nucleotide binding protein (G protein), q polypeptide
NCBI Organism
Homo sapiens
Other Product Names
GAQ, G-ALPHA-q, guanine nucleotide binding protein (G protein), q polypeptide, GNAQ, GAQ
Tested Applications
WB
Physical Properties
Liquid
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