PHC2 Antibody
Product Specifications
Background
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
1912
Swiss Prot
Q8IXK0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PHC2 (NP_004418.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HT-29
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=15-688
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
PHC2
Positive Control 2
HeLa
Positive Control 3
MCF7
Positive Control 4
Mouse brain
NCBI Official Name
Polyhomeotic homolog 2
NCBI Organism
Homo sapiens
Other Product Names
EDR2, HPH2, PH2, polyhomeotic-like protein 2, early development regulator 2 (homolog of polyhomeotic 2), early development regulatory protein 2, polyhomeotic 2, polyhomeotic-like 2
Tested Applications
WB
Physical Properties
Liquid
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