PHC2 Antibody

Product Specifications

Background

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

1912

Swiss Prot

Q8IXK0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PHC2 (NP_004418.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

Affinity purification

Positive Control

HT-29

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 37kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

PHC2

Positive Control 2

HeLa

Positive Control 3

MCF7

Positive Control 4

Mouse brain

NCBI Official Name

Polyhomeotic homolog 2

NCBI Organism

Homo sapiens

Other Product Names

EDR2, HPH2, PH2, polyhomeotic-like protein 2, early development regulator 2 (homolog of polyhomeotic 2), early development regulatory protein 2, polyhomeotic 2, polyhomeotic-like 2