ADRA1A Antibody
Product Specifications
Background
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
NCBI Gene ID
148
Swiss Prot
P35348
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 346-475 of human ADRA1A (NP_150646.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cell Cycle, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 51kDa
Fragment
IgG
Symbol
ADRA1A
Positive Control 2
LO2
Positive Control 3
HL-60
Positive Control 4
Mouse heart
Positive Control 5
Mouse kidney
Positive Control 6
Mouse spinal cord
NCBI Official Name
Adrenoceptor alpha 1A
NCBI Organism
Homo sapiens
Other Product Names
ADRA1A, adrenergic, alpha-1A-, receptor, ADRA1C, ADRA1L1, ALPHA1AAR, G protein coupled receptor, OTTHUMP00000125310, OTTHUMP00000125311, OTTHUMP00000125312, OTTHUMP00000125313, adrenergic, alpha-1A-, receptor variant 1, adrenergic, alpha-1A-, receptor var
Tested Applications
WB, IHC
Physical Properties
Liquid
Curated Selection
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