CA5A Antibody

Product Specifications

Background

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VA is localized in the mitochondria and expressed primarily in the liver. It may play an important role in ureagenesis and gluconeogenesis. CA5A gene maps to chromosome 16q24.3 and an unprocessed pseudogene has been assigned to 16p12-p11.2.

NCBI Gene ID

763

Swiss Prot

P35218

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 39-305 of human CA5A (NP_001730.1) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

Affinity purification

Positive Control

K-562

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 35kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

CA5A

Positive Control 2

LO2

Positive Control 3

HepG2

NCBI Official Name

Carbonic anhydrase 5A

NCBI Organism

Homo sapiens

Other Product Names

CA5D, CAV, CAVA, GS1-21A4.1, CA5A, carbonic anhydrase 5A, mitochondrial, CA-VA, carbonate dehydratase VA, carbonic anhydrase V, mitochondrial, carbonic anhydrase VA, mitochondrial, carbonic dehydratase