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FOSB Antibody

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

NCBI Gene ID

2354

Swiss Prot

P53539

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOSB (NP_006723.2) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Transcription

Purification

Affinity purification

Positive Control

U-87MG

Concentration

Batch dependent

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20˚ C. Avoid freeze / thaw cycles.

Calculated Molecular Weight

Observed: 37kDa

Fragment

IgG

Applications Notes

WB: 1:500 - 1:2000

Symbol

FOSB

Positive Control 2

SKOV3

Positive Control 3

HeLa

Positive Control 4

Mouse brain

Positive Control 5

Rat brain

NCBI Official Name

FBJ murine osteosarcoma viral oncogene homolog B

NCBI Organism

Homo sapiens

Other Product Names

FOSB, AP-1, G0S3, GOS3, GOSB

Tested Applications

WB

Physical Properties

Liquid

Frequently Asked Questions

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