FOSB Antibody
Product Specifications
Background
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2354
Swiss Prot
P53539
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human FOSB (NP_006723.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Transcription
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 37kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
FOSB
Positive Control 2
SKOV3
Positive Control 3
HeLa
Positive Control 4
Mouse brain
Positive Control 5
Rat brain
NCBI Official Name
FBJ murine osteosarcoma viral oncogene homolog B
NCBI Organism
Homo sapiens
Other Product Names
FOSB, AP-1, G0S3, GOS3, GOSB
Tested Applications
WB
Physical Properties
Liquid
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