GLI1 Antibody
Product Specifications
Background
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2735
Swiss Prot
P08151
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GLI1 (NP_001153517.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
DU145
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 130kDa/160kDa
Fragment
IgG
Symbol
GLI1
Positive Control 2
Mouse liver
Positive Control 3
Mouse brain
Positive Control 4
Rat brain
NCBI Official Name
GLI family zinc finger 1
NCBI Organism
Homo sapiens
Other Product Names
GLI1, GLI
Tested Applications
WB, IHC, IF
Physical Properties
Liquid
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